Publikationen des SFB 1525

Buck AK, Grigoleit GU, Kraus S, Schirbel A, Heinsch M, Dreher N, Higuchi T, Lapa C, Hänscheid H, Samnick S, Einsele H, Serfling SE, Werner RA (2023)
C-X-C Motif Chemokine Receptor 4-Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma.
The Journal of Nuclear Medicine (JNM) 2023 Jan; 64(1): 34-39
Zur Publikation

Chen Z, Väth M, Eckstein M, Delgobo M, Ramos G, Frantz S, Hofmann U, Gladow N (2023)
Characterization of the effect of the GLUT-1 inhibitor BAY-876 on T cells and macrophages.
Eur J Pharmacol. 2023 Feb 2;175552
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Delgobo M, Weiß E, Ashour D, Richter L, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Mariotti-Ferrandiz E, Rainer PP, Saliba AE, Ludewig B, Hofmann U, Frantz S and Campos Ramos G (2023)
Myocardial Milieu Favors Local Differentiation of Regulatory T Cells
Circulation ResearchVol. 132, No. 5
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Hartrampf PE, Kosmala A, Serfling SE, Bundschuh L, Higuchi T, Lapa C, Rowe SP, Matsusaka Y, Weich A, Buck AK, Bundschuh RA, Werner RA. (2023)
Interobserver Agreement Rates on C-X-C Motif Chemokine Receptor 4-Directed Molecular Imaging and Therapy.
Clin Nucl Med. 2023 Mar 22
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Klingenberg R, Holtkamp F, Grün D, Frey A, Jahns V, Jahns R, Gassenmaier T, Hamm CW, Frantz S, Keller T (2023)
Use of serial changes in biomarkers vs. baseline levels to predict left ventricular remodelling after STEMI.
ESC Heart Failure 2023 Feb; 10(1): 432-441
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Kosmala A, Serfling SE, Michalski K, Lindner T, Schirbel A, Higuchi T, Hartrampf PE, Derlin T, Buck AK, Weich A, Werner RA (2023)
Molecular imaging of arterial fibroblast activation protein: association with calcified plaque burden and cardiovascular risk factors.
Eur J Nucl Med Mol Imaging. 2023 May 6.
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Kosmala A, Serfling SE, Schlötelburg W, Lindner T, Michalski K, Schirbel A, Higuchi T, Hartrampf PE, Buck AK, Weich A, Werner RA. (2023)
High Interobserver Agreement on PSMA PET/CT Even in the Absence of Clinical Data.
Clin Nucl Med. 2023 Mar 1;48(3):207-212.
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Kosmala A, Serfling SE, Schlötelburg W, Lindner T, Michalski K, Schirbel A, Higuchi T, Hartrampf PE, Buck AK, Weich A, Werner RA (2023)
Impact of 68 Ga-FAPI-04 PET/CT on Staging and Therapeutic Management in Patients with Digestive System Tumors.
Clinical Nuclear Medicine 2023 Jan 1; 48(1): 35-42
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Li Y, Díaz I, Martín-Valls G, Beyersdorf N, Mateu E (2023)
Systemic CD4 cytotoxic T cells improve protection against PRRSV-1 transplacental infection.
Front Immunol. 2023 Jan 17;13:1020227
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Schütte JP, Manke MC, Hemmen K, Münzer P, Schörg BF, Ramos GC, Pogoda M, Dicenta V, Hoffmann SHL, Pinnecker J, Kollotzek F, Zdanyte M, Mueller KAL, Singh Y, Mack AF, Pichler B, Lang F, Nieswandt B, Gawaz M, Heinze KG, Casadei N, Borst O (2023)
Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia.
Circ Res. 2023 Mar 31
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Serfling SE, Hartrampf PE, Zhi Y, Higuchi T, Kosmala A, Serfling J, Schirbel A, Hörning A, Buck AK, Weich A, Werner RA. (2023)
Somatostatin Receptor-Directed PET/CT for Therapeutic Decision-Making and Disease Control in Patients Affected With Small Cell Lung Cancer.
Clin Nucl Med. 2023 Apr 1;48(4):309-314.
Zur Publikation

Terekhov M, Elabyad IA, Lohr D, Hofmann U, Schreiber LM. (2023)
High-resolution imaging of the excised porcine heart at a whole-body 7 T MRI system using an 8Tx/16Rx pTx coil.
MAGMA. 2023 Apr 7.
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Traub J, Frey A, Störk S. (2023)
Chronic Neuroinflammation and Cognitive Decline in Patients with Cardiac Disease: Evidence, Relevance, and Therapeutic Implications.
Life (Basel). 2023 Jan 24;13(2):329
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Traub J, Schürmann P, Schmitt D, Gassenmaier T, Fette G, Frantz S, Störk S, Beyersdorf N, Boivin-Jahns V, Jahns R, Hofmann U, Frey A (2023)
Features of metabolic syndrome and inflammation independently affect left ventricular function early after first myocardial infarction.
International Journal of Cardiology 2023 Jan 1; 370: 43-50
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Tutov A, Chen X, Werner RA, Mühlig S, Zimmermann T, Nose N, Koshino K, Lapa C, Decker M, Higuchi T. (2023)
Rationalizing the Binding Modes of PET Radiotracers Targeting the Norepinephrine Transporter.
Pharmaceutics. 2023 Feb 17;15(2):690.
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Weich A, Serfling SE, Rowe SP, Solnes LB, Buck AK, Higuchi T, Werner RA (2023)
Partial Response Upon Peptide Receptor Radionuclide Therapy in a Highly Proliferative Pancreatic Neuroendocrine Tumor.
Clin Nucl Med. 2023 Mar 16
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Weich A, Serfling SE, Yi H, Buck AK, Higuchi T, Werner RA. (2023)
Complete Remission Upon Peptide Receptor Radionuclide Therapy in a G2 Pancreatic Neuroendocrine Tumor.
Clin Nucl Med. 2023 Apr 1;48(4):335-336
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Brodehl A, Gerull B (2022)
Genetic Insights into Primary Restrictive Cardiomyopathy.
Journal of Clinical Medicine 2022 Apr 8; 11(8): 2094
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Brown HC, Beck S, Navarro S, Di Y, Soriano Jerez EM, Kaczmarzyk J, Thomas SG, Mirakaj V, Watson SP, Nieswandt B, Stegner D (2022)
Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model.
Blood Advances 2022 Aug: 2021006463  
No abstract available
Zur Publikation 

Chen X, Werner RA, Koshino K, Nose N, Mühlig S, Rowe SP, Pomper MG, Lapa C, Decker M, Higuchi T (2022)
A Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity – Introducing High NET Affinity PET Probe 18F-AF78.
Theranostics 2022 May 24; 12(9): 4446-4458
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Delgobo M, Weiß E, Ashour D, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Rainer P, Saliba AE, Ludewig B, Hofmann U, Frantz S, Campos Ramos G (2022)
Rapid differentiation of regulatory CD4+ T cells in the infarcted myocardium blunts in situ inflammation.
bioRxiv 2022 Mar 27
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Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ (2022)
Adult T-cells impair neonatal cardiac regeneration.
European Heart Journal 2022 Jul 21; 43(28): 2698-2709
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Erhard, F, Saliba AE, Lusser A, Toussaint C, Hennig T, Prusty BK, Kirschenbaum D, Abadie K, Miaka EA, Friedel CC, Amit I, Micura R, Dölken L (2022)
Time-resolved single-cell RNA-seq using metabolic RNA labelling.
Nature Revies Methods Primers 2022 Sep 29: 2(77) 
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Frantz S, Hundertmark MJ, Schulz-Menger J, Bengel FM, Bauersachs J (2022)
Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies.
European Heart Journal 2022 Jul 14; 43(27): 2549-2561
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Hapke N, Heinrichs M, Ashour D, Vogel E, Hofmann U, Frantz S, Campos Ramos G (2022)
Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction.
Journal of Molecular and Cellular Cardiology (JMCC) 2022 Dec; 173: 25-29
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Higuchi T, Serfling SE, Rowe SP, Werner RA (2022)
Therapeutic Effects of Lipid Lowering Medications on Myocardial Blood Flow, Inflammation, and Sympathetic Nerve Activity Using Nuclear Techniques.
Current Cardiology Reports 2022 Dec; 24(12): 1849-1853
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Higuchi T, Werner RA (2022)
Unfolding the cardioprotective potential of sigma-1 receptor-directed molecular imaging.
Editorial Journal of Nuclear Cardiology 2022 Aug 4
No abstract available
Zur Publikation

Hochrein SM, Wu H, Eckstein M, Arrigoni L, Herman JS, Schumacher F, Gerecke C, Rosenfeldt M, Grün D, Kleuser B, Gasteiger G, Kastenmüller W, Ghesquière B, Van den Bossche J, Abel ED, Vaeth M (2022)
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming.
Cell Metabolism 2022 Apr 5; 34(4): 516-532.e11
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Jeson Sangaralingham S, Kuhn M, Cannone V, Chen HH, Burnett JC (2022)
Natriuretic peptide pathways in heart failure - further therapeutic possibilities.
Cardiovascular Research 2022 Aug 25: 118(18): 3416-3433
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Lambertini A, Hartrampf PE, Higuchi T, Serfling SE, Meybohm P, Schirbel A, Buck AK, Werner RA (2022)
CXCR4-targeted molecular imaging after severe SARS-Cov-2 infection.
European Journal of Nuclear Medicine and Molecular Imaging 2022 Dec; 50(1): 228-229
Zur Publikation

Tolstik E, Gongalsky MB, Dierks J, Brand T, Pernecker M, Pervushin NV, Maksutova DE, Gonchar KA, Samsonova JV, Kopeina G, Sivakov V, Osminkina LA, Lorenz K (2022)
NEKAR study group. Raman and fluorescence micro-spectroscopy applied for the monitoring of sunitinib-loaded porous silicon nanocontainers in cardiac cells.
Frontiers of Pharmacology 2022 Aug 9; 13: 962763
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Matsusaka Y, Werner RA, Arias-Loza P, Nose N, Sasaki T, Chen X, Lapa C, Higuchi T (2022)
Performance Evaluation of a Preclinical SPECT Scanner with a Collimator Designed for Medium-Sized Animals.
Molecular Imaging 2022 Jul 16; 2022: 9810097Z
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Merches K, Breunig L, Fender J, Brand T, Bätz V, Idel S, Kollipara L, Reinders Y, Sickmann A, Mally A, Lorenz K (2022)
The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro.
Archives of Toxicology 2022 Aug; 96(8): 2341-2360
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Ramos CG, Hudecek M
The era of in vivo T cell engineering.
Med (N Y) 2022 Feb 11; 3(2): 85-86
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Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, Arias-Loza AP, Prinz M, Mack M, Schlepckow K, Haass C, Silvestre JS, Zernecke A, Saliba AE, Cochain C (2022)
Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction.
Cardiovascular Research 2022 Aug 11; cvac113
Zur Publikation

Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, Liu L, Ul Ain Q, Ehreiser V, Weber C, Kilani B, Mertsch P, Götschke J, Cremer S, Fu W, Lorenz M, Ishikawa-Ankerhold H, Raatz E, El-Nemr S, Görlach A, Marhuenda E, Stark K, Pircher J, Stegner D, Gieger C, Schmidt-Supprian M, Gaertner F, Almendros I, Kelm M, Schulz C, Hidalgo A, Massberg S (2022)
Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Immunity 2022 Dec 13; 55(12): 2285-2299
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Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L , Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M,  El-Armouche A (2022)
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Nature Communications 2022 Dec 10; 13(1): 7648
Zur Publikation

Tolstik E, Ali N, Guo S, Ebersbach P, Möllmann D, Arias-Loza P, Dierks J, Schuler I, Freier E, Debus J, Baba HA, Nordbeck P, Bocklitz T, Lorenz K (2022)
CARS Imaging Advances Early Diagnosis of Cardiac Manifestation of Fabry Disease.
International Journal of Molecular Sciences 2022 May 11; 23(10): 5345
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Traub J, Grondey K, Gassenmaier T, Schmitt D, Fette G, Frantz S, Boivin-Jahns V, Jahns R, Störk S, Stoll G, Reiter T, Hofmann U, Weber MS, Frey A (2022)
Sustained Increase in Serum Glial Fibrillary Acidic Protein after First ST-Elevation Myocardial Infarction.
International Journal of Molecular Sciences 2022 Sep 7; 23(18): 10304
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Traub J, Otto M, Sell R, Göpfert D, Homola G, Steinacker P, Oeckl P, Morbach C, Frantz S, Pham M, Störk S, Stoll G, Frey A (2022)
Serum phosphorylated tau protein 181 and neurofilament light chain in cognitively impaired heart failure patients.
Alzheimers´ Resarch and Therapy 2022 Oct 10; 14(1): 149
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Weiss LJ, Drayss M, Mott K, Droste M, Just B, Arold AM, Nieswandt B, Weismann D, Stegner D, Schulze H (2022)
The homophilic CD84 receptor is upregulated on platelets in COVID-19 and sepsis.
Thrombosis Research 2022 Dec; 220: 121-124
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Weiß E, Ramos GC, Delgobo M (2022)
Myocardial-Treg Crosstalk: How to Tame a Wolf.
Frontiers in Immunology 2022 May 25; 13: 914033
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Werner RA, Higuchi T, Nose N, Toriumi F, Matsusaka Y, Kuji I, Kazuhiro K (2022)
Generative adversarial network-created brain SPECTs of cerebral ischemia are indistinguishable to scans from real patients.
Scientific Reports 2022 Nov 5; 12(1): 18787
Zur Publikation 

Werner RA, Martinez RB, Marcus C, Kruse MJ, Sheikhbahaei S, Solnes LB, Higuchi T, Javadi MS, Rowe SP (2022)
Diagnostic performance of IQ·SPECT with high-speed scanning: A preliminary quality control study in obese patients.
Journal of Nuclear Cardiology. 2022 Dec; 29(6): 3443-3449
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Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba AE, Cochain C (2022)
Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis.
Cardiovascular Research 2022 Oct 3; cvac161
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