Clinical Trials
In clinical trials, new diagnostic and therapeutic methods as well as hypotheses about the predictability of therapy effectiveness are tested and validated. Within the scope of these trials, we cooperate with other hospitals, universities, and general practitioners.
Disruption of fear reconsolidation using rTMS in the treatment of anxiety disorders (SpiderMem)
In this study, we are investigating whether anxiety memory can be permanently erased from memory using transcanal magnetic stimulation.
Further information can be found on the page of the corresponding grant-funded project.
Treatment of major depressive disorders with bilateral theta-burst stimulation (TBS-D)
Depression is one of the most common and serious psychiatric disorders. In this study, the effectiveness of theta-burst stimulation (a form of magnetic stimulation) as an augmentative treatment for depression will be tested for its clinical efficacy.
A total of 236 patients will be enrolled in this study who will receive active or placebo stimulation. The treatment is carried out as an additional therapy on every working day for 6 weeks. The sustainability will be evaluated by 1 and 3 month follow-ups.
Further information can be found on the page of the corresponding grant-funded project.
P4D study
Fighting depression with personalised medicine
The project entitled "Personalised, predictive, precise and preventive medicine to improve the early detection, diagnosis, treatment and prevention of depressive disorders" (P4D) is the largest research project to date in Germany to improve the quality of depression treatment.
Further information can be found on the website of the associated grant-funded project
Computer-assisted risk evaluation in the early detection of psychotic illnesses (CARE)
CARE stands for computer-assisted risk evaluation and risk-adapted treatment in cases of increased risk of developing psychosis.
CARE is being carried out as a multi-centre, randomised controlled study, i.e. the people taking part are randomly assigned to the new clinical form of care or to the existing standard care. The aim is to use these measures to prevent the onset of psychosis and/or improve social and occupational performance.
What are psychoses?
sychoses describe a group of mental disorders that can occur independently, but also in conjunction with depressive or manic disorders or with the use of psychotropic substances. What the psychoses have in common, for example, is that the ego-environment boundary becomes blurred, the perception and interpretation of the world changes completely and changes in thinking can occur.
What is an increased risk of psychosis?
To date, we know that psychoses develop gradually over an average of 5.5 years, often beginning in adolescence or young adulthood in the form of distressing psychological symptoms. Those affected often seek help early on, but rarely find a specialised treatment offer promptly, as the first symptoms are usually unspecific and are not always recognised immediately.
Who can take part in CARE?
People between the ages of 16 and 40 who are at an increased risk of developing a psychotic disorder can take part in CARE. The study is not open to People with a pre-existing psychosis, severe depression with psychotic symptoms or with addictive disorders.
You can find more information
- in the flyer on the study
- on the website of the associated www.care-network.eu
tDCS treatment for ADHD
In this study tDCS will be reviewed as a non-invasive brain stimulation procedure in the sole or add-on treatment of attention-deficite hyperactivity disorder in adults. Currently subjects with already diagnosed ADHD are needed.
Interested parties should contact our study nurse:
Christiane Rieß
riess_@ukw.de
U-examination for children plus parents at the pediatrician to promote child development with impulses from gynaecological prenatal care (UPlusE)
Mental illnesses during pregnancy and breastfeeding are not uncommon and, if they are not treated or are treated too late, can lead to further serious problems for parents and children. Studies show that many of those affected are not diagnosed at an early stage and consequently do not receive adequate treatment or counseling.
As part of the UPlusE study, an app-based screening is being established for the early detection of depressive developments, psychosocial stress and problems in the parent-child relationship. Both (expectant) mothers and fathers are regularly surveyed at the end of pregnancy and in the first year of the child's life. These surveys are linked to the preventive check-ups at the gynecologist or U-examinations at the pediatrician. On the basis of this data, help is provided to those affected in line with their needs.
A digital network of gynecologists, pediatricians, psychiatrists, psychotherapists and psychosomaticians including obstetrics clinics and "early help" (Offers for families with children up to the age of three) should enable complex interdisciplinary and cross-sectoral care.
The aim of the study, which has received 4.6 million euros in funding from the Innovation Fund of the Joint Federal Committee, is to ensure that screening is included in the standard care provided by statutory health insurance funds and thus improve health in the long term.
Further information can be found at www.upluse.de, the corresponding UPlusE flyer and on the page of the associated grant-funded project.
PETE-Study
Mental illness - therapy - development
The aim of this study is to investigate the links between parental psychological stress and illness in the period around birth and child development. The study should also help to improve the diagnosis and treatment of mental illnesses around birth and thus promote healthy child development.
Further information can be found at the corresponding PETE flyer and on the page of the associated grant-funded project.
POSCOR
Further information can be found and on the page of the associated grant-funded project.
Behavioral and physical activation for multimorbid, elderly patients with depressive symptoms during the inpatient-outpatient transition (BRIDGE)
Around one in five older people is affected by depressive symptoms; the risk is even higher for people living at home and those with several illnesses at the same time (multimorbidity). However, when transitioning from geriatric psychiatric or geriatric inpatient or day clinic treatment to outpatient care, there is often a lack of support services to consolidate the therapeutic successes already achieved and prevent a renewed deterioration in health.
The aim of the BRIDGE project is to evaluate a new form of care to reduce depression in older, multimorbid people. The expertise of psychotherapeutic, exercise therapy and nursing specialists will be utilized. Those affected are encouraged and empowered to engage in physical activity and a positive daily routine. The program is planned for three months and follows a standardized modular treatment manual for behavioral and physical activation, whereby the specific design takes personal preferences into account. The care offered includes, for example, learning physical exercises based on the individual abilities of the participants, as well as links to regionally available health services. The care begins during inpatient or semi-inpatient treatment and is then continued at home by outreach nurses; in addition, the intervention is also made possible via video in the home environment.
BRIDGE is a joint project under the consortium leadership of the University Medical Center Mainz with study centers in Bavaria, Hesse, Rhineland-Palatinate and Saarland.
Project start for patients is 1.1.2025
Further information: Innovationsausschuss beim Gemeinsamen Bundesausschuss
Study on musical performance anxiety completed
Were you part of the scientific study on therapeutic support for performance anxiety?
Our study team is in the process of analysing and evaluating the data. As soon as the results are published, you will find them in the Psychiatry > Publications section. In addition, participants will be informed by email about any publications.
If you have any questions for the study team, please feel free to contact
to the study team at the Centre for Mental Health at the University Hospital of Würzburg by email to Auftrittsangst_VR@ukw.de
or to the University of Music, Würzburg, Ms Schröder, email: katja.schroeder@hfm-wuerzburg.de
Do you currently suffer from performance anxiety?
We are no longer accepting new subjects for the study. If you are experiencing significant problems due to your musical performance anxiety, we recommend that you seek psychotherapeutic help. You can find information about outpatient psychotherapy on the website of the Bavarian Chamber of Psychotherapists.